Pyrexia or Fever Causes, Symptoms, Diagnosis, Treatment

Pyrexia or Fever Causes, Symptoms, Diagnosis, Treatment

Pyrexia or Fever Causes, Symptoms, Diagnosis, Treatment

What is pyrexia 

Pyrexia describes and elevation in the body temperature above the normal range. It also known as fever, pyrexia is one of the ways our immune system respond in defending the body against infection. For a typical child, a normal body temperature is usually considered to be around 97.4°F (36.4°C), While the normal body temperature of an adult can be from 97 to 99°F

Generally, fever occurs when the body temperature rises above 100.4°F (38°C), Rivers of 104°F 40°C or higher may be extremely dangerous and demand prompt medical care. As they are viable of causing convulsion especially in infants, children and old people. Fever can be categorized based on its duration, severity and the pattern.

Duration of Pyrexia or Fever

A fever can be: Acute if it persists less than 7 days. An example of an acute fever is Malaria.
Sub-acute if it persists up to 2 weeks such as seen in typhoid fever.
Chronic or persistent, if it persists for more than 2 weeks such as tuberculosis.

Severity or height of fever
A fever can be: 
  • Mild or low grade, from 100.5- 102.2°F or  38.1 - 39°C
  • Moderate, from 102.3 to 104.0°F or 39.1 to 40°C
  • High, from 101.1 to 106.0°F or 40.1 to 41.1°C
  • Hyperpyrexia, greater than 106.0°F or 41.1°C
  • Hyperpyrexia, greater than 106.°F or 41.1°C

Pattern of Pyrexia or Fever

Infective endocarditis
  • Remittent fever, fever may come and go with fluctuation in temperature at a regular interval such as in infective endocarditis.
  • Continuous fever, fever fluctuate in a small variation of about 1 celsius in 24 hours such as in urinary tract infection.
  • Intermittent fever, fever comes down to normal each day such as in malaria. Intermittent favour is referred to as tertian fever when it persists for 48 hours and quotidian fever if it persists for 24 hours.
  • Relapsing fever, fever that reappears after a certain period of time.
  • Pel-Ebstein fever, fever that is dominant in people with Hodgkins’s lymphoma. Such a patient suffers from high fever for one week and low fever for the next week.
However, debate exists as to whether this type of pattern truly exists.

Causes of pyrexia or fever

Fever can be caused by Bacterial, viral and parasitic infection such as: Common cold, Malaria, Meningitis
A malignant tumer Certain medication such as antibiotics and drug used in high blood pressure or seizure treatment. Inflammatory conditions such as:
  • Rheumatoid arthritis
  • Lupus
  • Inflammatory bowel infection
  • Alcohol withdrawal
  • Dehydration
  • Overexposure to sunlight
  • Blood clots
  • Food poisoning
  • A side effect of vaccinations such as those used for tetanus
    • Use of illicit drugs such as cocaine
    • Cancer most especially
    • Kidney cancer
    • Leukemia
    • Lymphoma 
    • Metabolic disorder

Symptoms of pyrexia or fever 

Sickness behavior associated with fever may include:
  • Shivering
  • Lack of appetite
  • A headache
  • Sweating
  • Irritability
  • Dehydration 
  • Sleepiness
  • Lethargy
  • Inability to concentrate
  • Muscle and joint ache

Diagnosis and treatment of Pyrexia or fever 

  • Diagnosing fever is easy, the patient temperature is taken with a thermometer, a high reading is indicative of fever.
  • Diagnostics test such as Blood test, Urine test, X-ray and other imaging tests may be ordered depending on symptoms and medical history.
  • In young infants especially those younger than 28 days, fever can indicate a serious illness and the baby may need to be admitted into the hospital for testing and treatment.

Treatment of pyrexia or fever 

  • Treatment may depend on the cause of your fever 
  • If a bacterial infection is causing your fever, the doctor may prescribe antibiotics. Antibiotics have no effect against a virus, therefore, antiviral drugs may be used to treat certain viral infections.
  • Over the counter fever reducing medications such as acetaminophen (Tylenol), or ibuprofen (Motrin, Advil) may be recommended by the doctor. 
  • Fluid intake to avoid dehydration which can worsen the condition.


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